As research data proliferate across digital platforms, sequestration has become increasingly complex. At the same time, regulations require thorough documentation of what is sequestered and how the process is conducted. This panel brings together the perspectives of Research Integrity Officers and staff, IT professionals, and forensic consultants to explore how coordinated planning, communication, and collaboration can meet the current challenges of sequestration. Panelists will share practical strategies for locating, securing, and cataloging research data across diverse systems, offering attendees concrete approaches to strengthen their own institutional practices.